The purpose of this paper is to discuss how traditional homeopathic manufacturing reagents and processes couldgenerate the ability of a given potency to initiate nonlinear adaptive changes in an organism as a complex adaptive system (CAS) or network. As previously proposed,1e4 the homeopathic medicine (HM) would be a heterogeneous mixture of nano-sized particles (NPs, small particles that measure 1e100 nanometers along at least one dimension) of the source material, with or without the nonspecific presence of nanosilica released during succussions of solutions in borosilicate glassware.5 Other materials in solution also readily adsorb to, dope or seed silica NPs, thereby creating unique surface ‘defects’ and modifying their properties.6e
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